Effects of subarachnoid haemorrhage on intracranial prostaglandins.

Effects of hypertonic saline on intracranial pressure variables in subarachnoid haemorrhage patients

Norman Dott's contribution to aneurysm surgery.

Between 1926-36 Norman Dott managed 39 patients with suspected intracranial haemorrhage. During this period he established important principles of diagnosis and developed new methods for the medical and surgical treatment of aneurysmal subarachnoid haemorrhage. Dott performed the first intracranial operation to treat an aneurysm and the first angiogram to demonstrate an intracranial aneurysm. T...

Subarachnoid haemorrhage and intracranial aneurysms: what neurologists need to know.

The incidence of stroke caused by subarachnoid haemorrhage (SAH) remains constant, with intracranial aneurysm rupture causing SAH in up to 5000 patients in the UK per annum. Although this represents less than 5% of all strokes, recognition is of crucial importance since intervention can radically alter outcome. The combined mortality and morbidity for aneurysm rupture reaches 50%; since the con...

A Treatable Multiple Infarct Dementia

1. McKissock W, Paine K, Walsh L: Further observations on subarachnoid haemorrhage. J Neurol Neurosurg Psychiat 21: 239-248, 1958 2. McKissock W, Richardson A, Walsh L: "Posterior-communicating" aneurysms: Controlled trial of the conservative and surgical treatment of ruptured aneurysms of the internal carotid artery at or near the point of origin of the posterior communicating artery. Lancet 1...

The critical care management of poor-grade subarachnoid haemorrhage

Aneurysmal subarachnoid haemorrhage is a neurological syndrome with complex systemic complications. The rupture of an intracranial aneurysm leads to the acute extravasation of arterial blood under high pressure into the subarachnoid space and often into the brain parenchyma and ventricles. The haemorrhage triggers a cascade of complex events, which ultimately can result in early brain injury, d...